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  • Endocarditis is an infection of a heart valve, most often affecting the mitral or aortic valve. It can arise any time that bacteria enter the bloodstream, though it is more common when the heart valve has already been damaged for some other reason. The clinical signs of endocarditis are often nonspecific in the early stages, but may progress to include signs of heart failure later in the course of the disease. The diagnosis and treatment of endocarditis can present a challenge, requiring multiple tests and prolonged courses of antibiotic therapy.

  • Enilconazole is a topical wash/dip used to treat dermatophytosis (ring worm) in dogs and sometimes in cats. Side effects are uncommon as it is relatively well-tolerated, but in cats may include drooling, vomiting, lack of appetite, weight loss, muscle weakness, and elevated liver enzymes. Do not use in cats unless directed by your veterinarian. If a negative reaction occurs, please call your veterinary office.

  • Many veterinarians, including nutritionists and behaviorists, believe it is important for dogs and cats to express their natural foraging and hunting behaviors. For pets living indoors, this can be difficult, and the lack of this stimulation can sometimes lead to behavior problems. Enriching a pet's environment with food toys and puzzles at mealtimes can fulfill the need to forage. The use of toys, puzzles and other novel methods of food delivery can also be effective ways to increase daily movement in overweight or inactive pets.

  • Enrofloxacin is an antibiotic given by mouth or in the muscle commonly used to treat bacterial infections in cats, dogs, and off label in small mammals, birds, and reptiles. Common side effects include vomiting, diarrhea, and lack of appetite. It should not be used in growing or dehydrated pets, or in cats with kidney disease. Use cautiously in pets with seizures, liver, or kidney disease. If a negative reaction occurs, please call your veterinary office.

  • Enrofloxacin otic is applied topically and is labeled to treat ear infections in dogs. It is also used off-label to treat ear infections in cats. Give as directed. Side effects are rare but may include temporary hearing loss or skin reactions. Do not use with pets allergic to quinolones or sulfonamides, with young animals, or with those with central nervous system disorders. If a negative reaction occurs, please call the veterinary office.

  • Enzymatic toothpaste (brand name C.E.T., others) is a product used at home by pet owners to aid in tooth brushing that minimizes plaque and tartar formation on the exterior of the tooth (the crown), and also assists in the maintenance of good oral hygiene. It can be used on both dogs and cats.

  • Eosinophilic granuloma complex is a term used to describe three forms of skin lesions in cats including eosinophilic plaque, eosinophilic granuloma, and indolent ulcers. The lesions most commonly occur on the lip, sometimes resulting in disfigurement, but can also develop in the mouth or on other areas of the body.

  • Feline eosinophilic keratitis is a chronic inflammatory disease of the cornea that results in the surface of the eye appearing pink, white, or chalky. It is caused by an accumulation of inflammatory cells called eosinophils. The clinical signs, appearance, diagnosis, and treatment of this condition are explained in this handout.

  • Ephedrine is most commonly given by injection (and rarely by mouth) and is used off label to treat low blood pressure and certain types of urinary incontinence. Give as directed by your veterinarian. Common side effects include restlessness, fast heartbeat, and high blood pressure. Do not use in pets that are allergic to it or in pets with severe heart disease or abnormal heart rhythms. If a negative reaction occurs, please call your veterinary office.

  • Epineprhine is a drug used most often in emergency situations for animals (e.g., anaphylaxis, cardiopulmonary resuscitation/CPR). It may be added to local anesthesia drugs due to its ability to cause veins to constrict, thus delaying the body’s absorption of the drugs and prolonging the duration of the local anesthetic duration.