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  • Many herding breeds (most commonly Collies and Australian Shepherds) have a mutation at the MDR1 gene that makes them more sensitive to the negative effects of certain medications. These drugs include several antiparasitic agents (when given at high doses), the antidiarrheal agent loperamide (Imodium®), and several anticancer drugs. The effects of the mutation vary in severity, depending on whether the dog carries one or two copies of the mutation. There is a cheek swab or a commercially-available test that assesses blood samples for the presence of the MDR1 mutation.

  • Supportive braces can help dogs with many orthopedic conditions, including skeletal deformities, carpal hyperextension, and cruciate ligament disease. It is important to have any brace properly fitted to avoid complications. Braces are not considered equivalent to surgery for cruciate ligament disease.

  • Most cats instinctively hide their pain as a survival mechanism which can make detecting pain in cats a challenge. Although the signs may be subtle, careful observation of a cat’s everyday behaviors will often reveal pain when it is present. These signs may include changes in behavior, mobility, elimination, and grooming habits. Common pain medications include NSAIDs and opioids. Your veterinarian will choose the appropriate drugs based on your cat's specific needs.

  • Many dogs will instinctively hide their pain as a survival mechanism which in the past, led well-meaning experts to presume that dogs did not feel pain the same way humans do. Although the signs may be subtle, careful observation of a dog’s everyday behaviors will often reveal pain when it is present. These signs may include changes in behavior, mobility, and appetite. Common pain medications include NSAIDs, opioids, and other therapeutics. Your veterinarian will choose the appropriate drugs based on your dog’s specific needs.

  • Penetrating wounds can look minor on the surface but may cause severe injury below the skin. A thorough assessment requires sedation or anesthesia and surgery may be required to address the extent of the injury. This handout outlines first aid steps a pet owner can take while transporting their injured pet to the veterinary hospital.

  • Pneumothorax is an accumulation of air outside the lungs, but inside the chest wall. The air outside the lung prevents the lungs from inflating normally, and can lead to lung collapse. There are several variations of pneumothorax.

  • When your cat comes home after an operation, special care must be taken to ensure he remains indoors with restricted activity and cannot lick or chew at his incision site. Monitor your cat for abnormal signs and contact your veterinarian if any are observed.

  • Pulsed electromagnetic field (PEMF) therapy is the use of a generated electromagnetic field to affect changes in tissues of the body. PEMF is believed to have beneficial pain-relieving and healing effects but definitive clinical evidence or a positive benefit is currently lacking. Potential benefits and contraindications are discussed.

  • Pyelonephritis is an upper urinary tract infection involving the kidneys and ureters. Many cats have no clinical signs when they have pyelonephritis, although they may have signs of lower urinary tract disease. Pyelonephritis is usually caused by a bacterial infection that moves up the urinary tract from the bladder to the kidneys. Cats with sudden pyelonephritis do well and return to normal health unless concurrent complications exist.

  • Radiation is a type of energy produced naturally by the sun, earth, and rocks and artificially by machines. Although several types of tumors can be treated with radiation therapy alone (e.g., nasal tumors, brain tumors, and certain types of lymphoma), radiation therapy is most commonly used to destroy or limit the growth of cancer cells left behind (i.e., microscopic disease) after a tumor has been surgically removed. Side effects depend on the type and location of the tumor and its surrounding tissues.